Panzomist DSR
Pantoprazole Sodium IP (as gastro-resistant pellets) 40 mg + Domperidone IP (as prolonged-release pellets) 30 mg
Rx GastroenterologyPanzomic 40
Panzomic 40
Pantoprazole Sodium IP equivalent to Pantoprazole 40 mg
40 mg
Indications
- Gastro-oesophageal reflux disease, including erosive reflux oesophagitis and maintenance of healing
- Duodenal ulcer and benign gastric ulcer
- NSAID-associated gastric mucosal injury, including protection in patients on continued NSAID therapy
- Helicobacter pylori eradication, as the acid-suppressing component of a combination regimen
- Pathological acid hypersecretory states such as Zollinger-Ellison syndrome
Contraindications
- Known hypersensitivity to pantoprazole or to other substituted benzimidazole proton pump inhibitors
- Co-administration with rilpivirine, and with antiretrovirals whose absorption depends on gastric acid such as atazanavir and nelfinavir
- Severe hepatic impairment, where exposure rises and specialist review is required
- Should not be used to mask undiagnosed alarm features such as unintended weight loss, dysphagia, recurrent vomiting or gastrointestinal bleeding, which need investigation first
Side effects
- Headache, diarrhoea, constipation, flatulence, abdominal pain and nausea
- Dry mouth, dizziness, skin rash or itching
- With prolonged use: low serum magnesium, reduced vitamin B12 absorption and an increased risk of hip, wrist and spine fracture
- Uncommon to rare: severe cutaneous reactions, acute interstitial nephritis, raised liver enzymes and Clostridioides difficile-associated diarrhoea
Important: This information is provided for educational purposes only and is not a substitute for professional medical advice. Please consult a Registered Medical Practitioner before starting, stopping, or changing any medication. Manufactured and marketed under Indian DCGI regulations.
Product information sheet
Frequently asked questions
What is Panzomic 40 tablet used for?
Panzomic 40 is prescribed for acid-related disorders of the upper gastrointestinal tract: gastro-oesophageal reflux disease and reflux oesophagitis, duodenal and gastric ulcer, gastric injury caused by anti-inflammatory painkillers, and as part of Helicobacter pylori eradication therapy. It reduces the amount of acid the stomach produces rather than neutralising acid already present.
Is Panzomic 40 the same as pantoprazole injection?
The active molecule and the 40 mg strength are the same, but the presentation is not. The injection is given intravenously in hospital when a patient cannot swallow, is vomiting, or is being treated for a bleeding ulcer. Panzomic 40 is the oral tablet used in clinic and at home, including when a patient is stepped down from injectable therapy. Which form is appropriate is a decision for the treating physician.
Can Panzomic 40 be taken for a long period?
Long-term proton pump inhibitor therapy is common in reflux maintenance and in patients on continuous NSAID treatment, but it is not risk-free. Extended use has been linked to low magnesium, vitamin B12 deficiency and a higher fracture risk, so treatment should be reviewed periodically and continued only for as long as your physician directs.
Related Products
More from the same therapeutic area.